Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many malignant tumors.However, ICI-induced hyper-immune activation causes cardiotoxicity.Traditional treatments such as glucocorticoids and immunosuppressants have limited effectiveness and may even accelerate tumor growth.This study aimed to identify approaches tha
This paper presented a novel bond-slip model to better reveal the mechanical behavior of the bolt-grout interface for fully-grouted rockbolts under tensile loads by considering the non-linear response in the softening stage.The exponential decay function is adopted for describing the non-linear response in the softening stage.Based on the improved
Interventions for job interviews targeting the impaired theory of mind observed in individuals with autism spectrum disorders (ASD) are limited.We developed a role-play-based guidance system for job interviews using an android Equine - Barn Supplies - Buckets robot resembling a real person.Individuals with ASD worked in pairs and played dual roles
Summary: The objective of this study is to develop a device to mimic a microfluidic system of human arterial blood vessels.The device combines fluid shear stress (FSS) and cyclic stretch (CS), which are resulting from blood flow and blood pressure, SCALP RENEW respectively.The device can reveal real-time observation of dynamic morphological change